Current Issue : April - June Volume : 2018 Issue Number : 2 Articles : 5 Articles
It is estimated by theWorld Health Organization (WHO) that most of the worldââ?¬â?¢s population depends on herbal medicine for their\nhealth care. Nigella sativa (N. sativa), also known as black-caraway and as ââ?¬Å?Kalonji,ââ?¬Â is a well-known seed all over theworld. It is one\nof the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil,\nsuch as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine,\nand alpha-hederin. Due to these numerous important ingredients it was found that it affects different areas of our body and has\nmany pharmacological effects as antibacterial, antiviral, anti-inflammatory, and wound healing effect and also for acne vulgaris,\nskin cancer, pigmentation, andmany cosmeceutical applications. Based on the folklore usage of N. sativa seeds and oil, they are used\nin various systems of food and medicines. The aim of this article is to provide a detailed survey of the literature of cosmeceutical\nand external applications of N. sativa which is expected to stimulate further studies on this subject....
Castanea sativa fruit processing generates high amounts of by-products, mostly bur.\nCurrently, the cosmetic industry has a great interest in natural extracts as antioxidant sources.\nIn the present study, C. sativa bur extract was used as the active ingredient, in different amounts,\nin topical hydrogels. The formulations were characterized regarding total phenolic and flavonoid\ncontents (TPC and TFC, respectively), antioxidant activity (DPPH radical scavenging capacity and\nferric reducing antioxidant power (FRAP)) and technological and microbiological properties. The\nsame parameters were evaluated after 30 days of storage at 4 ââ??¦C (T30/4\nââ??¦C) and 20 ââ??¦C (T30/20\nââ??¦C).\nAt time 0 (T0), the TPC ranged between 0.79 and 9.65 mg of gallic acid equivalents (GAE)/g gel,\nwhile TFC varied from 0.05 to 1.23 mg of catechin equivalents (CAE)/g gel. Antioxidant activity\nwas high for both assays, with values at T0 ranging between 98.41 and 1013.43 Ã?¼mol of ferrous\nsulphate equivalents (FSE)/g gel and varying between 431.96 and 990.84 Ã?¼g of Trolox equivalents\n(TE)/g gel for FRAP and DPPH assays, respectively. No formulation exceeded the defined criteria\nin microbiological counts. All formulations showed similar technological profiles but particular\nattention should be given to pH. The gel with 50% of extract (F3) was selected as the best one for\npotential cosmetic applications....
Resveratrol is a natural substance that has been the target of many researchers over the\nyears since it presents a variety of potential applications in the areas of cosmetics and medicine\nas a treatment for some diseases. Due to its high antioxidant capacity but low bioavailability,\nwe evaluated the antiaging potential of resveratrol as a liotropic liquid crystal emulsion. Initially, we\nperformed in vitro assays to quantify both the organoleptic characteristics and stability of the\nemulsion. Next, an in vivo trial was performed on the faces of 30 volunteers to determine the\ncream�s cosmetic potential and to measure porphyrins, skin barrier function, skin pigmentation,\nexpression lines, and porosity. The emulsion maintained its characteristics during the in vitro assays\nand, in the in vivo trial, it had some effect only on pore size in forehead, without any significant\neffects on the other parameters. We had 6 dropouts throughout the study, then the final number\nof volunteers was 24. Most volunteers did not show any changes in skin pigmentation throughout\nthe study. Similarly, there was not any noticeable improvement on any other parameters evaluated.\nHowever, volunteers related a high level of satisfaction with the product....
The perennial and widespread herb Lythrum salicaria L., also called purple loosestrife, is a\nplant that is traditionally used in European medicine. Purple loosestrife is known for its ability to\ntreat internal disorders, such as gastrointestinal issues or hemorrhages. Our objective was to take\nanother look on this natural source of ellagitannins in terms of biological activities. Exploration of\nthe phytochemical content of an extract of aerial parts of Lythrum salicaria L. was completed before\ninitiating research on its biological effects towards keratinocytes, reconstructed epidermis, and skins.\nThe potential of the natural compounds were evaluated by topical treatment of reconstructed tissues.\nThe extract and one of its major compounds were able to act as pro-differentiating and protecting\nagents towards skin cells by stimulating the expressions of markers taking part in the structure\nof epidermis and dermis. Also, the extract showed beneficial effects on the global morphology of\nthe skin. Thus, Lythrum salicaria L. constitutes a new natural source for the development of active\ningredients for the dermo-cosmetic field....
Although eye area cosmetics contain preservatives, contamination can still occur during or\nafter manufacture or through use. Understanding the likelihood of bacterial survival in eye creams\nbegins with sensitive and accurate methods for the detection of bacterial contamination; therefore,\nwe investigated optimal culture conditions, including neutralizers, dilution broths, and selective\nmedia for the detection of Bacillus in eye cream. Samples of three different brands of eye creams\nwere first mixed with Tween 80, Tween 20, or a blend of Tween 60 and Span 80, then neutralized and\nnon-neutralized samples were individually inoculated with B. cereus strains, B. mycoides, a mislabeled\nB. megaterium, B. subtilis or B. thuringiensis at a final concentration of 5 log CFU/g. The inoculated\nsamples, with and without neutralizers, were spiral-plated and incubated at 30 ââ??¦C for 24 h to\n48 h. Presumptive colonies of Bacillus were enumerated on U. S. Food and Drug Administration\nBacteriological Analytical Manual (FDA-BAM) referenced agars Bacillus cereus rapid agar (BACARA)\nand mannitol-egg yolk-polymixin agar (MYP). Our results show significant differences among the\nneutralizers, plates, and products. The combination of Tryptone- Azolectin-Tween and Tween 80\n(TAT and T80) produced higher levels of Bacillus, estimated at 4.18 log CFU/g compared to growth\non Modified letheen broth and Tween 80, which produced 3.97 log CFU/g (P < 0.05). Colony counts\nof B. cereus cells on MYP agar were significantly higher, than those on BACARA agar, showing\nan average of 4.25 log CFU/g versus 3.84 log CFU/g, respectively (P < 0.05). The growth of the\nstrain mislabeled B. megaterium ATCC 6458 on B. cereus selective agars BACARA and MYP agar\nled us to further investigations. We identified bi-pyramidal crystals among colonies of the strain,\nand subsequent PCR identified the cry 1 gene, indicating that strain was actually B. thuringiensis\nsubps. kurstaki....
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